Which commandment is primarily concerned with the sanctity of life?

The Sixth Commandment is primarily concerned with the sanctity of life as it commands, "You shall not murder." This directive emphasizes the value of human life, indicating that life is sacred and should not be taken unjustly. The moral implications of this commandment extend beyond mere physical acts of killing; they encompass attitudes and actions that can harm or devalue human life, such as anger and hatred.

In the context of the other commandments, while the Fourth Commandment relates to the Sabbath and worship, the Fifth Commandment focuses on honoring one's parents, and the Seventh Commandment addresses issues of fidelity in marriage. These commandments, while important, do not primarily address the core principle of the sanctity of life in the same manner that the Sixth Commandment does. Thus, the Sixth Commandment stands out as the one that directly relates to the intrinsic value and dignity of human life.